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Genome-wide Analysis of Transcription Factor E2F1 Mutant Proteins Reveals That N- and C-terminal Protein Interaction Domains Do Not Participate in Targeting E2F1 to the Human Genome

Previous studies of E2F family members have suggested that protein-protein interactions may be the mechanism by which E2F proteins are recruited to specific genomic regions. We have addressed this hypothesis on a genome-wide scale using ChIP-seq analysis of MCF7 cell lines that express tagged wild t...

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Detalles Bibliográficos
Autores principales:	Cao, Alina R., Rabinovich, Roman, Xu, Maoxiong, Xu, Xiaoqin, Jin, Victor X., Farnham, Peggy J.
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2011
Materias:	Genomics and Proteomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069401/ https://www.ncbi.nlm.nih.gov/pubmed/21310950 http://dx.doi.org/10.1074/jbc.M110.217158

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