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Relationship between Prion Propensity and the Rates of Individual Molecular Steps of Fibril Assembly
Peptides and proteins possess an inherent propensity to self-assemble into generic fibrillar nanostructures known as amyloid fibrils, some of which are involved in medical conditions such as Alzheimer disease. In certain cases, such structures can self-propagate in living systems as prions and trans...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069414/ https://www.ncbi.nlm.nih.gov/pubmed/21233211 http://dx.doi.org/10.1074/jbc.M110.208934 |