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Crystal Structure of the Human N-Myc Downstream-regulated Gene 2 Protein Provides Insight into Its Role as a Tumor Suppressor

Considerable attention has recently been paid to the N-Myc downstream-regulated gene (NDRG) family because of its potential as a tumor suppressor in many human cancers. Primary amino acid sequence information suggests that the NDRG family proteins may belong to the α/β-hydrolase (ABH) superfamily; h...

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Detalles Bibliográficos
Autores principales: Hwang, Jungwon, Kim, Yoonjeong, Kang, Ho Bum, Jaroszewski, Lukasz, Deacon, Ashley M., Lee, Hwiseop, Choi, Won-Chan, Kim, Kyung-Jin, Kim, Cheol-Hee, Kang, Beom Sik, Lee, Jie-Oh, Oh, Tae-Kwang, Kim, Jae Wha, Wilson, Ian A., Kim, Myung Hee
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069448/
https://www.ncbi.nlm.nih.gov/pubmed/21247902
http://dx.doi.org/10.1074/jbc.M110.170803