PDE4D and PDE4B Function in Distinct Subcellular Compartments in Mouse Embryonic Fibroblasts

Signaling through cAMP regulates most cellular functions. The spatiotemporal control of cAMP is, therefore, crucial for differential regulation of specific cellular targets. Here we investigated the consequences of PDE4B or PDE4D gene ablation on cAMP signaling at a subcellular level using mouse emb...

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Detalles Bibliográficos
Autores principales: Blackman, Brigitte E., Horner, Kathleen, Heidmann, Julia, Wang, Dan, Richter, Wito, Rich, Thomas C., Conti, Marco
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069460/
https://www.ncbi.nlm.nih.gov/pubmed/21288894
http://dx.doi.org/10.1074/jbc.M110.203604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069460/
https://www.ncbi.nlm.nih.gov/pubmed/21288894
http://dx.doi.org/10.1074/jbc.M110.203604

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