Cargando…
PDE4D and PDE4B Function in Distinct Subcellular Compartments in Mouse Embryonic Fibroblasts
Signaling through cAMP regulates most cellular functions. The spatiotemporal control of cAMP is, therefore, crucial for differential regulation of specific cellular targets. Here we investigated the consequences of PDE4B or PDE4D gene ablation on cAMP signaling at a subcellular level using mouse emb...
Autores principales: | Blackman, Brigitte E., Horner, Kathleen, Heidmann, Julia, Wang, Dan, Richter, Wito, Rich, Thomas C., Conti, Marco |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069460/ https://www.ncbi.nlm.nih.gov/pubmed/21288894 http://dx.doi.org/10.1074/jbc.M110.203604 |
Ejemplares similares
-
Conserved expression and functions of PDE4 in rodent and human heart
por: Richter, Wito, et al.
Publicado: (2010) -
Roles of GRK and PDE4 Activities in the Regulation of β(2) Adrenergic Signaling
por: Xin, Wenkuan, et al.
Publicado: (2008) -
Assessment of PDE4 Inhibitor-Induced Hypothermia as a Correlate of Nausea in Mice
por: Boyd, Abigail, et al.
Publicado: (2021) -
Signaling from β(1)- and β(2)-adrenergic receptors is defined by differential interactions with PDE4
por: Richter, Wito, et al.
Publicado: (2008) -
Acute PDE4 Inhibition Induces a Transient Increase in Blood Glucose in Mice
por: Irelan, Daniel, et al.
Publicado: (2023)