Recent advances in the CRANK software suite for experimental phasing

For its first release in 2004, CRANK was shown to effectively detect and phase anomalous scatterers from single-wavelength anomalous diffraction data. Since then, CRANK has been significantly improved and many more structures can be built automatically with single- or multiple-wavelength anomalous d...

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Detalles Bibliográficos
Autores principales: Pannu, Navraj S., Waterreus, Willem-Jan, Skubák, Pavol, Sikharulidze, Irakli, Abrahams, Jan Pieter, de Graaff, Rudolf A. G.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069748/
https://www.ncbi.nlm.nih.gov/pubmed/21460451
http://dx.doi.org/10.1107/S0907444910052224
Descripción
Sumario:For its first release in 2004, CRANK was shown to effectively detect and phase anomalous scatterers from single-wavelength anomalous diffraction data. Since then, CRANK has been significantly improved and many more structures can be built automatically with single- or multiple-wavelength anomalous diffraction or single isomorphous replacement with anomalous scattering data. Here, the new algorithms that have been developed that have led to these substantial improvements are discussed and CRANK’s performance on over 100 real data sets is shown. The latest version of CRANK is freely available for download at http://www.bfsc.leidenuniv.nl/software/crank/ and from CCP4 (http://www.ccp4.ac.uk/).

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