Comparison of KRAS and EGFR gene status between primary non-small cell lung cancer and local lymph node metastases: implications for clinical practice

BACKGROUND: Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKI) have been widely used for the treatment of non-small cell lung cancer (NSCLC). KRAS and EGFR somatic mutations in NSCLC may predict resistance and responsiveness to TKI, respectively. Nevertheless, most research to da...

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Detalles Bibliográficos
Autores principales: Sun, Leina, Zhang, Qiang, Luan, Huanling, Zhan, Zhongli, Wang, Changli, Sun, Baocun
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069944/
https://www.ncbi.nlm.nih.gov/pubmed/21414214
http://dx.doi.org/10.1186/1756-9966-30-30

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