Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study

OBJECTIVES: The genetic aetiology of osteoarthritis has not yet been elucidated. To enable a well-powered genome-wide association study (GWAS) for osteoarthritis, the authors have formed the arcOGEN Consortium, a UK-wide collaborative effort aiming to scan genome-wide over 7500 osteoarthritis cases...

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Detalles Bibliográficos
Autores principales: Panoutsopoulou, K, Southam, L, Elliott, K S, Wrayner, N, Zhai, G, Beazley, C, Thorleifsson, G, Arden, N K, Carr, A, Chapman, K, Deloukas, P, Doherty, M, McCaskie, A, Ollier, W E R, Ralston, S H, Spector, T D, Valdes, A M, Wallis, G A, Wilkinson, J M, Arden, E, Battley, K, Blackburn, H, Blanco, F J, Bumpstead, S, Cupples, L A, Day-Williams, A G, Dixon, K, Doherty, S A, Esko, T, Evangelou, E, Felson, D, Gomez-Reino, J J, Gonzalez, A, Gordon, A, Gwilliam, R, Halldorsson, B V, Hauksson, V B, Hofman, A, Hunt, S E, Ioannidis, J P A, Ingvarsson, T, Jonsdottir, I, Jonsson, H, Keen, R, Kerkhof, H J M, Kloppenburg, M G, Koller, N, Lakenberg, N, Lane, N E, Lee, A T, Metspalu, A, Meulenbelt, I, Nevitt, M C, O'Neill, F, Parimi, N, Potter, S C, Rego-Perez, I, Riancho, J A, Sherburn, K, Slagboom, P E, Stefansson, K, Styrkarsdottir, U, Sumillera, M, Swift, D, Thorsteinsdottir, U, Tsezou, A, Uitterlinden, A G, van Meurs, J B J, Watkins, B, Wheeler, M, Mitchell, S, Zhu, Y, Zmuda, J M, Zeggini, E, Loughlin, J
Formato: Texto
Lenguaje:English
Publicado: BMJ Group 2010
Materias:
Basic and Translational Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070286/
https://www.ncbi.nlm.nih.gov/pubmed/21177295
http://dx.doi.org/10.1136/ard.2010.141473

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