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The Driving Force of the Na(+)/Ca(2+)-Exchanger during Metabolic Inhibition

Objective: Metabolic inhibition causes a decline in mechanical performance and, if prolonged, myocardial contracture and cell death. The decline in mechanical performance is mainly due to altered intracellular calcium handling, which is under control of the Na(+)/Ca(2+)-exchanger (NCX) The driving f...

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Detalles Bibliográficos
Autores principales: Baartscheer, Antonius, Schumacher, Cees A., Coronel, Ruben, Fiolet, Jan W. T.
Formato: Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070476/
https://www.ncbi.nlm.nih.gov/pubmed/21483726
http://dx.doi.org/10.3389/fphys.2011.00010