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The Driving Force of the Na(+)/Ca(2+)-Exchanger during Metabolic Inhibition
Objective: Metabolic inhibition causes a decline in mechanical performance and, if prolonged, myocardial contracture and cell death. The decline in mechanical performance is mainly due to altered intracellular calcium handling, which is under control of the Na(+)/Ca(2+)-exchanger (NCX) The driving f...
Autores principales: | Baartscheer, Antonius, Schumacher, Cees A., Coronel, Ruben, Fiolet, Jan W. T. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070476/ https://www.ncbi.nlm.nih.gov/pubmed/21483726 http://dx.doi.org/10.3389/fphys.2011.00010 |
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