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Environmental and Genetic Stressors and the Unfolded Protein Response in Exocrine Pancreatic Function – A Hypothesis
The exocrine pancreas has the greatest protein synthetic capacity of any mammalian organ and is challenged with the synthesis, processing and transporting a large load of digestive enzymes. Based on recent findings we present a hypothesis proposing that mutations in the digestive enzymes and environ...
Autores principales: | Pandol, Stephen J., Gorelick, Fred S., Lugea, Aurelia |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070477/ https://www.ncbi.nlm.nih.gov/pubmed/21483727 http://dx.doi.org/10.3389/fphys.2011.00008 |
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