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Positive Allosteric Modulators of Type 5 Metabotropic Glutamate Receptors (mGluR5) and Their Therapeutic Potential for the Treatment of CNS Disorders

Studies utilizing selective pharmacological antagonists or targeted gene deletion have demonstrated that type 5 metabotropic glutamate receptors (mGluR5) are critical mediators and potential therapeutic targets for the treatment of numerous disorders of the central nervous system (CNS), including de...

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Detalles Bibliográficos
Autores principales: Cleva, Richard M., Olive, M. Foster
Formato: Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070661/
https://www.ncbi.nlm.nih.gov/pubmed/21368721
http://dx.doi.org/10.3390/molecules16032097

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