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Disease-Related Changes in the Cerebrospinal Fluid Metabolome in Amyotrophic Lateral Sclerosis Detected by GC/TOFMS

BACKGROUND/AIM: The changes in the cerebrospinal fluid (CSF) metabolome associated with the fatal neurodegenerative disease amyotrophic lateral sclerosis (ALS) are poorly understood and earlier smaller studies have shown conflicting results. The metabolomic methodology is suitable for screening larg...

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Detalles Bibliográficos
Autores principales: Wuolikainen, Anna, Moritz, Thomas, Marklund, Stefan L., Antti, Henrik, Andersen, Peter Munch
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070699/
https://www.ncbi.nlm.nih.gov/pubmed/21483737
http://dx.doi.org/10.1371/journal.pone.0017947