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MDL28170, a Calpain Inhibitor, Affects Trypanosoma cruzi Metacyclogenesis, Ultrastructure and Attachment to Rhodnius prolixus Midgut

BACKGROUND: Trypanosoma cruzi is the etiological agent of Chagas' disease. During the parasite life cycle, many molecules are involved in the differentiation process and infectivity. Peptidases are relevant for crucial steps of T. cruzi life cycle; as such, it is conceivable that they may parti...

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Detalles Bibliográficos
Autores principales: Ennes-Vidal, Vítor, Menna-Barreto, Rubem F. S., Santos, André L. S., Branquinha, Marta H., d'Avila-Levy, Claudia M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070728/
https://www.ncbi.nlm.nih.gov/pubmed/21483751
http://dx.doi.org/10.1371/journal.pone.0018371