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Neuronal stimulation with 5-hydroxytryptamine 4 receptor induces anti-inflammatory actions via α7nACh receptors on muscularis macrophages associated with postoperative ileus
BACKGROUND: The main symptom of postoperative ileus (POI) is an intestinal motility disorder in which monocytes/macrophages and neutrophils play crucial roles. Prokinetic 5-hydroxytryptamine 4 receptor (5-HT(4)R) agonists and dopamine receptor antagonists are potential therapeutic agents for directl...
Autores principales: | Tsuchida, Yasuaki, Hatao, Fumihiko, Fujisawa, Masahiko, Murata, Takahisa, Kaminishi, Michio, Seto, Yasuyuki, Hori, Masatoshi, Ozaki, Hiroshi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BMJ Group
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071096/ https://www.ncbi.nlm.nih.gov/pubmed/21115544 http://dx.doi.org/10.1136/gut.2010.227546 |
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