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L-Type calcium channel blockade reduces network activity in human epileptic hypothalamic hamartoma tissue
PURPOSE: Human hypothalamic hamartomas (HHs) are associated with gelastic seizures, intrinsically epileptogenic, and notoriously refractory to medical therapy. We previously reported that the L-type calcium channel antagonist nifedipine blocks spontaneous firing and γ-aminobutyric acid (GABA)(A)–ind...
Autores principales: | Simeone, Kristina A, Sabesan, Shivkumar, Kim, Do Young, Kerrigan, John F, Rho, Jong M, Simeone, Timothy A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071288/ https://www.ncbi.nlm.nih.gov/pubmed/21269296 http://dx.doi.org/10.1111/j.1528-1167.2010.02942.x |
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