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Targeting adenovirus gene delivery to activated tumour-associated vasculature via endothelial selectins
Clinical experience with adenovirus vectors has highlighted the need for improved delivery and targeting. Tumour-associated endothelium offers an additional mechanism for enhanced viral uptake into tumours which is accessible for systemic gene delivery. Building on expertise in using polymer ‘stealt...
Autores principales: | Bachtarzi, Houria, Stevenson, Mark, Šubr, Vladimir, Ulbrich, Karel, Seymour, Leonard W., Fisher, Kerry D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science Publishers
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071491/ https://www.ncbi.nlm.nih.gov/pubmed/20965218 http://dx.doi.org/10.1016/j.jconrel.2010.10.011 |
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