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HIV Infection Enhances TRAIL-Induced Cell Death in Macrophage by Down-Regulating Decoy Receptor Expression and Generation of Reactive Oxygen Species

BACKGROUND: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) could induce apoptosis of HIV-1-infected monocyte-derived macrophage (MDM), but the molecular mechanisms are not well understood. METHODOLOGY/PRINCIPAL FINDINGS: By using an HIV-1 Env-pseudotyped virus (HIV-1 PV)-infected MD...

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Detalles Bibliográficos
Autores principales:	Zhu, Dan-Ming, Shi, Juan, Liu, Shilian, Liu, Yanxin, Zheng, Dexian
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071698/ https://www.ncbi.nlm.nih.gov/pubmed/21483669 http://dx.doi.org/10.1371/journal.pone.0018291

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