FGF signalling through RAS/MAPK and PI3K pathways regulates cell movement and gene expression in the chicken primitive streak without affecting E-cadherin expression

BACKGROUND: FGF signalling regulates numerous aspects of early embryo development. During gastrulation in amniotes, epiblast cells undergo an epithelial to mesenchymal transition (EMT) in the primitive streak to form the mesoderm and endoderm. In mice lacking FGFR1, epiblast cells in the primitive s...

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Detalles Bibliográficos
Autores principales: Hardy, Katharine M, Yatskievych, Tatiana A, Konieczka, JH, Bobbs, Alexander S, Antin, Parker B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071786/
https://www.ncbi.nlm.nih.gov/pubmed/21418646
http://dx.doi.org/10.1186/1471-213X-11-20

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