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Long Telomeres are Preferentially Extended During Recombination-Mediated Telomere Maintenance
Most human somatic cells do not express telomerase. Consequently, with each cell division their telomeres progressively shorten until replicative senescence is induced. Approximately 15% of human cancers maintain their telomeres using telomerase-independent, recombination-based mechanisms collective...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071861/ https://www.ncbi.nlm.nih.gov/pubmed/21441915 http://dx.doi.org/10.1038/nsmb.2034 |