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The role of the proteasome in the generation of MHC class I ligands and immune responses
The ubiquitin–proteasome system (UPS) degrades intracellular proteins into peptide fragments that can be presented by major histocompatibility complex (MHC) class I molecules. While the UPS is functional in all mammalian cells, its subunit composition differs depending on cell type and stimuli recei...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
SP Birkhäuser Verlag Basel
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071949/ https://www.ncbi.nlm.nih.gov/pubmed/21387144 http://dx.doi.org/10.1007/s00018-011-0657-y |