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Intestinal epithelial stem cells do not protect their genome by asymmetric chromosome segregation
The idea that stem cells of adult tissues with high turnover are protected from DNA replication-induced mutations by maintaining the same 'immortal' template DNA strands together through successive divisions has been tested in several tissues. In the epithelium of the small intestine, the...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072071/ https://www.ncbi.nlm.nih.gov/pubmed/21448157 http://dx.doi.org/10.1038/ncomms1260 |