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Oral Propranolol for Circumscribed Choroidal Hemangioma

INTRODUCTION: Several therapeutic approaches have been developed to treat choroidal hemangioma. However, all these therapies are associated with a potential risk of damaging the overlying retina. CASE REPORT: We report a case of circumscribed choroidal hemangioma (CCH) in a 59-year-old man refractor...

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Autores principales: Sanz-Marco, Empar, Gallego, Roberto, Diaz-Llopis, Manuel
Formato: Texto
Lenguaje:English
Publicado: S. Karger AG 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072177/
https://www.ncbi.nlm.nih.gov/pubmed/21475606
http://dx.doi.org/10.1159/000325142
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author Sanz-Marco, Empar
Gallego, Roberto
Diaz-Llopis, Manuel
author_facet Sanz-Marco, Empar
Gallego, Roberto
Diaz-Llopis, Manuel
author_sort Sanz-Marco, Empar
collection PubMed
description INTRODUCTION: Several therapeutic approaches have been developed to treat choroidal hemangioma. However, all these therapies are associated with a potential risk of damaging the overlying retina. CASE REPORT: We report a case of circumscribed choroidal hemangioma (CCH) in a 59-year-old man refractory to laser treatment. Visual acuity was 20/200 and a serous macular detachment was present. The CCH was treated with oral propanolol, whereupon visual acuity improved to 20/20 and the macular detachment resolved without systemic or local adverse effects. DISCUSSION: Propanolol is a β-blocker commonly used in cardiology that may induce endothelium vasoconstriction and inhibit endothelial proliferation. It has been shown to be effective in infantile facial hemangiomas, and proved safe and effective for the CCH in our patient. Further studies are needed to confirm our observation.
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spelling pubmed-30721772011-04-07 Oral Propranolol for Circumscribed Choroidal Hemangioma Sanz-Marco, Empar Gallego, Roberto Diaz-Llopis, Manuel Case Rep Ophthalmol Published: February 2011 INTRODUCTION: Several therapeutic approaches have been developed to treat choroidal hemangioma. However, all these therapies are associated with a potential risk of damaging the overlying retina. CASE REPORT: We report a case of circumscribed choroidal hemangioma (CCH) in a 59-year-old man refractory to laser treatment. Visual acuity was 20/200 and a serous macular detachment was present. The CCH was treated with oral propanolol, whereupon visual acuity improved to 20/20 and the macular detachment resolved without systemic or local adverse effects. DISCUSSION: Propanolol is a β-blocker commonly used in cardiology that may induce endothelium vasoconstriction and inhibit endothelial proliferation. It has been shown to be effective in infantile facial hemangiomas, and proved safe and effective for the CCH in our patient. Further studies are needed to confirm our observation. S. Karger AG 2011-02-25 /pmc/articles/PMC3072177/ /pubmed/21475606 http://dx.doi.org/10.1159/000325142 Text en Copyright © 2011 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published: February 2011
Sanz-Marco, Empar
Gallego, Roberto
Diaz-Llopis, Manuel
Oral Propranolol for Circumscribed Choroidal Hemangioma
title Oral Propranolol for Circumscribed Choroidal Hemangioma
title_full Oral Propranolol for Circumscribed Choroidal Hemangioma
title_fullStr Oral Propranolol for Circumscribed Choroidal Hemangioma
title_full_unstemmed Oral Propranolol for Circumscribed Choroidal Hemangioma
title_short Oral Propranolol for Circumscribed Choroidal Hemangioma
title_sort oral propranolol for circumscribed choroidal hemangioma
topic Published: February 2011
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072177/
https://www.ncbi.nlm.nih.gov/pubmed/21475606
http://dx.doi.org/10.1159/000325142
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