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Successful Function-Preserving Therapy for Chondroblastoma of the Temporal Bone Involving the Temporomandibular Joint

We present a case involving a late diagnosis of chondroblastoma of the temporal skull base involving the temporomandibular joint (TMJ). Following an initial misdiagnosis and unsuccessful treatment over a period of 5 years, the patient was referred to our department for further evaluation and possibl...

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Autores principales: Yokoyama, Junkichi, Yoshimoto, Hitoshi, Ito, Shin, Ohba, Shinichi, Fujimaki, Mitsuhisa, Ikeda, Katsuhisa, Yazawa, Masaki, Fujimiya, Nozomi, Hanaguri, Makoto
Formato: Texto
Lenguaje:English
Publicado: S. Karger AG 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072183/
https://www.ncbi.nlm.nih.gov/pubmed/21475594
http://dx.doi.org/10.1159/000324640
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author Yokoyama, Junkichi
Yoshimoto, Hitoshi
Ito, Shin
Ohba, Shinichi
Fujimaki, Mitsuhisa
Ikeda, Katsuhisa
Yazawa, Masaki
Fujimiya, Nozomi
Hanaguri, Makoto
author_facet Yokoyama, Junkichi
Yoshimoto, Hitoshi
Ito, Shin
Ohba, Shinichi
Fujimaki, Mitsuhisa
Ikeda, Katsuhisa
Yazawa, Masaki
Fujimiya, Nozomi
Hanaguri, Makoto
author_sort Yokoyama, Junkichi
collection PubMed
description We present a case involving a late diagnosis of chondroblastoma of the temporal skull base involving the temporomandibular joint (TMJ). Following an initial misdiagnosis and unsuccessful treatment over a period of 5 years, the patient was referred to our department for further evaluation and possible surgical intervention for occlusal abnormalities, trismus, clicking of the TMJ, and hearing impairment. Based on preoperative immunochemical studies showing positive reaction of multinucleated giant cells for S-100 protein, the final diagnosis was chondroblastoma. The surgical approach – postauricular incision and total parotidectomy, with complete removal of the temporal bone, including the TMJ via the extended middle fossa – was successful in preserving facial nerves and diminishing clinical manifestations. This study highlights a misdiagnosed case in an effort to underline the importance of medical examinations and accurate differential diagnosis in cases involving any tumor mass in the temporal bone.
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spelling pubmed-30721832011-04-07 Successful Function-Preserving Therapy for Chondroblastoma of the Temporal Bone Involving the Temporomandibular Joint Yokoyama, Junkichi Yoshimoto, Hitoshi Ito, Shin Ohba, Shinichi Fujimaki, Mitsuhisa Ikeda, Katsuhisa Yazawa, Masaki Fujimiya, Nozomi Hanaguri, Makoto Case Rep Oncol Published: February 2011 We present a case involving a late diagnosis of chondroblastoma of the temporal skull base involving the temporomandibular joint (TMJ). Following an initial misdiagnosis and unsuccessful treatment over a period of 5 years, the patient was referred to our department for further evaluation and possible surgical intervention for occlusal abnormalities, trismus, clicking of the TMJ, and hearing impairment. Based on preoperative immunochemical studies showing positive reaction of multinucleated giant cells for S-100 protein, the final diagnosis was chondroblastoma. The surgical approach – postauricular incision and total parotidectomy, with complete removal of the temporal bone, including the TMJ via the extended middle fossa – was successful in preserving facial nerves and diminishing clinical manifestations. This study highlights a misdiagnosed case in an effort to underline the importance of medical examinations and accurate differential diagnosis in cases involving any tumor mass in the temporal bone. S. Karger AG 2011-02-14 /pmc/articles/PMC3072183/ /pubmed/21475594 http://dx.doi.org/10.1159/000324640 Text en Copyright © 2011 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published: February 2011
Yokoyama, Junkichi
Yoshimoto, Hitoshi
Ito, Shin
Ohba, Shinichi
Fujimaki, Mitsuhisa
Ikeda, Katsuhisa
Yazawa, Masaki
Fujimiya, Nozomi
Hanaguri, Makoto
Successful Function-Preserving Therapy for Chondroblastoma of the Temporal Bone Involving the Temporomandibular Joint
title Successful Function-Preserving Therapy for Chondroblastoma of the Temporal Bone Involving the Temporomandibular Joint
title_full Successful Function-Preserving Therapy for Chondroblastoma of the Temporal Bone Involving the Temporomandibular Joint
title_fullStr Successful Function-Preserving Therapy for Chondroblastoma of the Temporal Bone Involving the Temporomandibular Joint
title_full_unstemmed Successful Function-Preserving Therapy for Chondroblastoma of the Temporal Bone Involving the Temporomandibular Joint
title_short Successful Function-Preserving Therapy for Chondroblastoma of the Temporal Bone Involving the Temporomandibular Joint
title_sort successful function-preserving therapy for chondroblastoma of the temporal bone involving the temporomandibular joint
topic Published: February 2011
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072183/
https://www.ncbi.nlm.nih.gov/pubmed/21475594
http://dx.doi.org/10.1159/000324640
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