Pure Small Cell Carcinoma of the Prostate: A Case Report and Literature Review

Primary small cell carcinoma of the prostate (SCPCa) is a rare pathologic entity with unique clinical features and a poor prognosis. We present a case of a patient diagnosed with pure SCPCa treated with a combined chemo-radiotherapeutic approach. Pathological findings showed that the neoplastic cell...

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Detalles Bibliográficos
Autores principales: Capizzello, Antonio, Peponi, Evangelia, Simou, Nafsika, Ntaskagiannis, Dimitrios, Tasiou, Ifigenia, Kamina, Sevasti, Tsekeris, Periklis
Formato: Texto
Lenguaje:English
Publicado: S. Karger AG 2011
Materias:
Published: February 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072185/
https://www.ncbi.nlm.nih.gov/pubmed/21475596
http://dx.doi.org/10.1159/000324717
Descripción
Sumario:Primary small cell carcinoma of the prostate (SCPCa) is a rare pathologic entity with unique clinical features and a poor prognosis. We present a case of a patient diagnosed with pure SCPCa treated with a combined chemo-radiotherapeutic approach. Pathological findings showed that the neoplastic cells exhibited positivity for pancytokeratin, synaptophysin, thyroid transcription factor-1 and CD56. Immunostaining for prostate-specific antigen was negative, while serum prostate-specific antigen was within normal limits. We review the available literature to gain additional information about diagnosis, treatment and prognosis of pure SCPCa.

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