Pure Small Cell Carcinoma of the Prostate: A Case Report and Literature Review

Primary small cell carcinoma of the prostate (SCPCa) is a rare pathologic entity with unique clinical features and a poor prognosis. We present a case of a patient diagnosed with pure SCPCa treated with a combined chemo-radiotherapeutic approach. Pathological findings showed that the neoplastic cell...

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Autores principales: Capizzello, Antonio, Peponi, Evangelia, Simou, Nafsika, Ntaskagiannis, Dimitrios, Tasiou, Ifigenia, Kamina, Sevasti, Tsekeris, Periklis
Formato: Texto
Lenguaje:English
Publicado: S. Karger AG 2011
Materias:
Published: February 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072185/
https://www.ncbi.nlm.nih.gov/pubmed/21475596
http://dx.doi.org/10.1159/000324717
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author Capizzello, Antonio
Peponi, Evangelia
Simou, Nafsika
Ntaskagiannis, Dimitrios
Tasiou, Ifigenia
Kamina, Sevasti
Tsekeris, Periklis
author_facet Capizzello, Antonio
Peponi, Evangelia
Simou, Nafsika
Ntaskagiannis, Dimitrios
Tasiou, Ifigenia
Kamina, Sevasti
Tsekeris, Periklis
author_sort Capizzello, Antonio
collection PubMed
description Primary small cell carcinoma of the prostate (SCPCa) is a rare pathologic entity with unique clinical features and a poor prognosis. We present a case of a patient diagnosed with pure SCPCa treated with a combined chemo-radiotherapeutic approach. Pathological findings showed that the neoplastic cells exhibited positivity for pancytokeratin, synaptophysin, thyroid transcription factor-1 and CD56. Immunostaining for prostate-specific antigen was negative, while serum prostate-specific antigen was within normal limits. We review the available literature to gain additional information about diagnosis, treatment and prognosis of pure SCPCa.
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spelling pubmed-30721852011-04-07 Pure Small Cell Carcinoma of the Prostate: A Case Report and Literature Review Capizzello, Antonio Peponi, Evangelia Simou, Nafsika Ntaskagiannis, Dimitrios Tasiou, Ifigenia Kamina, Sevasti Tsekeris, Periklis Case Rep Oncol Published: February 2011 Primary small cell carcinoma of the prostate (SCPCa) is a rare pathologic entity with unique clinical features and a poor prognosis. We present a case of a patient diagnosed with pure SCPCa treated with a combined chemo-radiotherapeutic approach. Pathological findings showed that the neoplastic cells exhibited positivity for pancytokeratin, synaptophysin, thyroid transcription factor-1 and CD56. Immunostaining for prostate-specific antigen was negative, while serum prostate-specific antigen was within normal limits. We review the available literature to gain additional information about diagnosis, treatment and prognosis of pure SCPCa. S. Karger AG 2011-02-16 /pmc/articles/PMC3072185/ /pubmed/21475596 http://dx.doi.org/10.1159/000324717 Text en Copyright © 2011 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published: February 2011
Capizzello, Antonio
Peponi, Evangelia
Simou, Nafsika
Ntaskagiannis, Dimitrios
Tasiou, Ifigenia
Kamina, Sevasti
Tsekeris, Periklis
Pure Small Cell Carcinoma of the Prostate: A Case Report and Literature Review
title Pure Small Cell Carcinoma of the Prostate: A Case Report and Literature Review
title_full Pure Small Cell Carcinoma of the Prostate: A Case Report and Literature Review
title_fullStr Pure Small Cell Carcinoma of the Prostate: A Case Report and Literature Review
title_full_unstemmed Pure Small Cell Carcinoma of the Prostate: A Case Report and Literature Review
title_short Pure Small Cell Carcinoma of the Prostate: A Case Report and Literature Review
title_sort pure small cell carcinoma of the prostate: a case report and literature review
topic Published: February 2011
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072185/
https://www.ncbi.nlm.nih.gov/pubmed/21475596
http://dx.doi.org/10.1159/000324717
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