A Case of Disseminated and Fulminant Plasmacytomas That Developed during Bortezomib Treatment

Multiple myeloma is an incurable and slow growing plasma cell neoplasm. The introduction of new drugs has increased the number of treatment options. Bortezomib, the first-in-class proteasome inhibitor, has been shown to have a significant antitumor activity in the treatment of relapse/refractory pat...

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Autores principales: Bae, Soo-Young, Ahn, Jae-Sook, Yang, Deok-Hwan, Kim, Yeo-Kyeoung, Min, Jung-Joon, Song, Ho-Chun, Bom, Hee-Seung, Jeong, Yong Yeon, Kim, Hyeoung-Joon, Lee, Je-Jung
Formato: Texto
Lenguaje:English
Publicado: S. Karger AG 2011
Materias:
Published: February 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072187/
https://www.ncbi.nlm.nih.gov/pubmed/21475598
http://dx.doi.org/10.1159/000324920
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author Bae, Soo-Young
Ahn, Jae-Sook
Yang, Deok-Hwan
Kim, Yeo-Kyeoung
Min, Jung-Joon
Song, Ho-Chun
Bom, Hee-Seung
Jeong, Yong Yeon
Kim, Hyeoung-Joon
Lee, Je-Jung
author_facet Bae, Soo-Young
Ahn, Jae-Sook
Yang, Deok-Hwan
Kim, Yeo-Kyeoung
Min, Jung-Joon
Song, Ho-Chun
Bom, Hee-Seung
Jeong, Yong Yeon
Kim, Hyeoung-Joon
Lee, Je-Jung
author_sort Bae, Soo-Young
collection PubMed
description Multiple myeloma is an incurable and slow growing plasma cell neoplasm. The introduction of new drugs has increased the number of treatment options. Bortezomib, the first-in-class proteasome inhibitor, has been shown to have a significant antitumor activity in the treatment of relapse/refractory patients with multiple myeloma. Additionally, plasmacytomas have shown significant response to bortezomib. In this case report, we describe a patient who developed disseminated and fulminant extramedullary plasmacytomas during combination chemotherapy treatment with bortezomib within a short period, after having shown clinical improvement.
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spelling pubmed-30721872011-04-07 A Case of Disseminated and Fulminant Plasmacytomas That Developed during Bortezomib Treatment Bae, Soo-Young Ahn, Jae-Sook Yang, Deok-Hwan Kim, Yeo-Kyeoung Min, Jung-Joon Song, Ho-Chun Bom, Hee-Seung Jeong, Yong Yeon Kim, Hyeoung-Joon Lee, Je-Jung Case Rep Oncol Published: February 2011 Multiple myeloma is an incurable and slow growing plasma cell neoplasm. The introduction of new drugs has increased the number of treatment options. Bortezomib, the first-in-class proteasome inhibitor, has been shown to have a significant antitumor activity in the treatment of relapse/refractory patients with multiple myeloma. Additionally, plasmacytomas have shown significant response to bortezomib. In this case report, we describe a patient who developed disseminated and fulminant extramedullary plasmacytomas during combination chemotherapy treatment with bortezomib within a short period, after having shown clinical improvement. S. Karger AG 2011-02-25 /pmc/articles/PMC3072187/ /pubmed/21475598 http://dx.doi.org/10.1159/000324920 Text en Copyright © 2011 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published: February 2011
Bae, Soo-Young
Ahn, Jae-Sook
Yang, Deok-Hwan
Kim, Yeo-Kyeoung
Min, Jung-Joon
Song, Ho-Chun
Bom, Hee-Seung
Jeong, Yong Yeon
Kim, Hyeoung-Joon
Lee, Je-Jung
A Case of Disseminated and Fulminant Plasmacytomas That Developed during Bortezomib Treatment
title A Case of Disseminated and Fulminant Plasmacytomas That Developed during Bortezomib Treatment
title_full A Case of Disseminated and Fulminant Plasmacytomas That Developed during Bortezomib Treatment
title_fullStr A Case of Disseminated and Fulminant Plasmacytomas That Developed during Bortezomib Treatment
title_full_unstemmed A Case of Disseminated and Fulminant Plasmacytomas That Developed during Bortezomib Treatment
title_short A Case of Disseminated and Fulminant Plasmacytomas That Developed during Bortezomib Treatment
title_sort case of disseminated and fulminant plasmacytomas that developed during bortezomib treatment
topic Published: February 2011
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072187/
https://www.ncbi.nlm.nih.gov/pubmed/21475598
http://dx.doi.org/10.1159/000324920
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