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Extended Venous Thromboembolism Prophylaxis for High-Risk Patients Undergoing Surgery for Malignancy

BACKGROUND: In surgical patients with known malignancy, the odds ratio for an episode of a venous thromboembolism is approximately 6.5 compared to a group of patients without malignancy undergoing the same procedure [Heit et al.: Arch Intern Med 2000;160:809–815]. CASE REPORT: We present a case of a...

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Autores principales: Perre, A., Markman, M.
Formato: Texto
Lenguaje:English
Publicado: S. Karger AG 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072189/
https://www.ncbi.nlm.nih.gov/pubmed/21475600
http://dx.doi.org/10.1159/000324584
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author Perre, A.
Markman, M.
author_facet Perre, A.
Markman, M.
author_sort Perre, A.
collection PubMed
description BACKGROUND: In surgical patients with known malignancy, the odds ratio for an episode of a venous thromboembolism is approximately 6.5 compared to a group of patients without malignancy undergoing the same procedure [Heit et al.: Arch Intern Med 2000;160:809–815]. CASE REPORT: We present a case of a 46-year-old Caucasian male with a history of adenocarcinoma of the rectum. The patient received neoadjuvant treatment prior to low anterior resection with diverting colostomy. He received short-term prophylaxis for venous thrombosis, but unfortunately developed a blood clot in a lower extremity several weeks after surgery. CONCLUSION: There is a well-defined role in carefully selected patients for the use of extended prophylaxis to prevent venous thromboembolic complications following cancer surgery.
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spelling pubmed-30721892011-04-07 Extended Venous Thromboembolism Prophylaxis for High-Risk Patients Undergoing Surgery for Malignancy Perre, A. Markman, M. Case Rep Oncol Published: February 2011 BACKGROUND: In surgical patients with known malignancy, the odds ratio for an episode of a venous thromboembolism is approximately 6.5 compared to a group of patients without malignancy undergoing the same procedure [Heit et al.: Arch Intern Med 2000;160:809–815]. CASE REPORT: We present a case of a 46-year-old Caucasian male with a history of adenocarcinoma of the rectum. The patient received neoadjuvant treatment prior to low anterior resection with diverting colostomy. He received short-term prophylaxis for venous thrombosis, but unfortunately developed a blood clot in a lower extremity several weeks after surgery. CONCLUSION: There is a well-defined role in carefully selected patients for the use of extended prophylaxis to prevent venous thromboembolic complications following cancer surgery. S. Karger AG 2011-02-25 /pmc/articles/PMC3072189/ /pubmed/21475600 http://dx.doi.org/10.1159/000324584 Text en Copyright © 2011 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published: February 2011
Perre, A.
Markman, M.
Extended Venous Thromboembolism Prophylaxis for High-Risk Patients Undergoing Surgery for Malignancy
title Extended Venous Thromboembolism Prophylaxis for High-Risk Patients Undergoing Surgery for Malignancy
title_full Extended Venous Thromboembolism Prophylaxis for High-Risk Patients Undergoing Surgery for Malignancy
title_fullStr Extended Venous Thromboembolism Prophylaxis for High-Risk Patients Undergoing Surgery for Malignancy
title_full_unstemmed Extended Venous Thromboembolism Prophylaxis for High-Risk Patients Undergoing Surgery for Malignancy
title_short Extended Venous Thromboembolism Prophylaxis for High-Risk Patients Undergoing Surgery for Malignancy
title_sort extended venous thromboembolism prophylaxis for high-risk patients undergoing surgery for malignancy
topic Published: February 2011
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072189/
https://www.ncbi.nlm.nih.gov/pubmed/21475600
http://dx.doi.org/10.1159/000324584
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