Possible Clinical Significance of Serum Soluble Interleukin-2 Receptor Level in Primary Bone Lymphoma: Two Case Reports

In two patients with primary bone lymphoma (PBL) treated in our clinic, serum levels of soluble interleukin-2 receptor (sIL-2R) reflected the clinical course. In both cases, sIL-2R levels were high before treatment and normalized with the therapeutic effects of chemotherapy, coinciding with the chan...

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Autores principales: Yabe, Hiroki, Ueno, Hironori, Ochi, Kensuke, Morioka, Hideo, Yabe, Hiroo, Terai, Chihiro
Formato: Texto
Lenguaje:English
Publicado: S. Karger AG 2011
Materias:
Published: March 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072191/
https://www.ncbi.nlm.nih.gov/pubmed/21475602
http://dx.doi.org/10.1159/000325399
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author Yabe, Hiroki
Ueno, Hironori
Ochi, Kensuke
Morioka, Hideo
Yabe, Hiroo
Terai, Chihiro
author_facet Yabe, Hiroki
Ueno, Hironori
Ochi, Kensuke
Morioka, Hideo
Yabe, Hiroo
Terai, Chihiro
author_sort Yabe, Hiroki
collection PubMed
description In two patients with primary bone lymphoma (PBL) treated in our clinic, serum levels of soluble interleukin-2 receptor (sIL-2R) reflected the clinical course. In both cases, sIL-2R levels were high before treatment and normalized with the therapeutic effects of chemotherapy, coinciding with the changes in lactate dehydrogenase levels and radiographic findings. Adding to the recently reported results of the diagnostic ability of sIL-2R in PBL, our case study highlights the clinical significance of serum sIL-2R levels as a tumor marker in PBL cases.
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spelling pubmed-30721912011-04-07 Possible Clinical Significance of Serum Soluble Interleukin-2 Receptor Level in Primary Bone Lymphoma: Two Case Reports Yabe, Hiroki Ueno, Hironori Ochi, Kensuke Morioka, Hideo Yabe, Hiroo Terai, Chihiro Case Rep Oncol Published: March 2011 In two patients with primary bone lymphoma (PBL) treated in our clinic, serum levels of soluble interleukin-2 receptor (sIL-2R) reflected the clinical course. In both cases, sIL-2R levels were high before treatment and normalized with the therapeutic effects of chemotherapy, coinciding with the changes in lactate dehydrogenase levels and radiographic findings. Adding to the recently reported results of the diagnostic ability of sIL-2R in PBL, our case study highlights the clinical significance of serum sIL-2R levels as a tumor marker in PBL cases. S. Karger AG 2011-03-04 /pmc/articles/PMC3072191/ /pubmed/21475602 http://dx.doi.org/10.1159/000325399 Text en Copyright © 2011 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published: March 2011
Yabe, Hiroki
Ueno, Hironori
Ochi, Kensuke
Morioka, Hideo
Yabe, Hiroo
Terai, Chihiro
Possible Clinical Significance of Serum Soluble Interleukin-2 Receptor Level in Primary Bone Lymphoma: Two Case Reports
title Possible Clinical Significance of Serum Soluble Interleukin-2 Receptor Level in Primary Bone Lymphoma: Two Case Reports
title_full Possible Clinical Significance of Serum Soluble Interleukin-2 Receptor Level in Primary Bone Lymphoma: Two Case Reports
title_fullStr Possible Clinical Significance of Serum Soluble Interleukin-2 Receptor Level in Primary Bone Lymphoma: Two Case Reports
title_full_unstemmed Possible Clinical Significance of Serum Soluble Interleukin-2 Receptor Level in Primary Bone Lymphoma: Two Case Reports
title_short Possible Clinical Significance of Serum Soluble Interleukin-2 Receptor Level in Primary Bone Lymphoma: Two Case Reports
title_sort possible clinical significance of serum soluble interleukin-2 receptor level in primary bone lymphoma: two case reports
topic Published: March 2011
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072191/
https://www.ncbi.nlm.nih.gov/pubmed/21475602
http://dx.doi.org/10.1159/000325399
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