Cerebellar Degeneration as Presenting Symptom of Recurrent Endometrial Stromal Sarcoma with Sex-Cord Elements

We report a 66-year-old woman with slowly progressive ataxia due to cerebellar atrophy. Imaging studies revealed multiple lesions in both the lungs and dorsal subpleural space. A biopsy identified the lesions as metastases of a low-grade endometrial stromal sarcoma containing sex-cord elements. The...

Descripción completa

Detalles Bibliográficos
Autores principales: Gliem, Michael, Panayotopoulos, Dimitris, Feindt, Peter, Heikaus, Sebastian, Fleisch, Markus C., Seitz, Rüdiger J.
Formato: Texto
Lenguaje:English
Publicado: S. Karger AG 2011
Materias:
Published: February 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072195/
https://www.ncbi.nlm.nih.gov/pubmed/21490714
http://dx.doi.org/10.1159/000324927
_version_ 1782201522358059008
author Gliem, Michael
Panayotopoulos, Dimitris
Feindt, Peter
Heikaus, Sebastian
Fleisch, Markus C.
Seitz, Rüdiger J.
author_facet Gliem, Michael
Panayotopoulos, Dimitris
Feindt, Peter
Heikaus, Sebastian
Fleisch, Markus C.
Seitz, Rüdiger J.
author_sort Gliem, Michael
collection PubMed
description We report a 66-year-old woman with slowly progressive ataxia due to cerebellar atrophy. Imaging studies revealed multiple lesions in both the lungs and dorsal subpleural space. A biopsy identified the lesions as metastases of a low-grade endometrial stromal sarcoma containing sex-cord elements. The histological appearance was identical to a uterine tumor the patient was treated for with hysterectomy 16 years before. The metastases were removed surgically, and after 3 months ataxia had regressed. We conclude that the presenting cerebellar degeneration in this patient resulted from the metastatic recurrence of the endometrial tumor.
format Text
id pubmed-3072195
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher S. Karger AG
record_format MEDLINE/PubMed
spelling pubmed-30721952011-04-13 Cerebellar Degeneration as Presenting Symptom of Recurrent Endometrial Stromal Sarcoma with Sex-Cord Elements Gliem, Michael Panayotopoulos, Dimitris Feindt, Peter Heikaus, Sebastian Fleisch, Markus C. Seitz, Rüdiger J. Case Rep Neurol Published: February 2011 We report a 66-year-old woman with slowly progressive ataxia due to cerebellar atrophy. Imaging studies revealed multiple lesions in both the lungs and dorsal subpleural space. A biopsy identified the lesions as metastases of a low-grade endometrial stromal sarcoma containing sex-cord elements. The histological appearance was identical to a uterine tumor the patient was treated for with hysterectomy 16 years before. The metastases were removed surgically, and after 3 months ataxia had regressed. We conclude that the presenting cerebellar degeneration in this patient resulted from the metastatic recurrence of the endometrial tumor. S. Karger AG 2011-02-21 /pmc/articles/PMC3072195/ /pubmed/21490714 http://dx.doi.org/10.1159/000324927 Text en Copyright © 2011 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published: February 2011
Gliem, Michael
Panayotopoulos, Dimitris
Feindt, Peter
Heikaus, Sebastian
Fleisch, Markus C.
Seitz, Rüdiger J.
Cerebellar Degeneration as Presenting Symptom of Recurrent Endometrial Stromal Sarcoma with Sex-Cord Elements
title Cerebellar Degeneration as Presenting Symptom of Recurrent Endometrial Stromal Sarcoma with Sex-Cord Elements
title_full Cerebellar Degeneration as Presenting Symptom of Recurrent Endometrial Stromal Sarcoma with Sex-Cord Elements
title_fullStr Cerebellar Degeneration as Presenting Symptom of Recurrent Endometrial Stromal Sarcoma with Sex-Cord Elements
title_full_unstemmed Cerebellar Degeneration as Presenting Symptom of Recurrent Endometrial Stromal Sarcoma with Sex-Cord Elements
title_short Cerebellar Degeneration as Presenting Symptom of Recurrent Endometrial Stromal Sarcoma with Sex-Cord Elements
title_sort cerebellar degeneration as presenting symptom of recurrent endometrial stromal sarcoma with sex-cord elements
topic Published: February 2011
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072195/
https://www.ncbi.nlm.nih.gov/pubmed/21490714
http://dx.doi.org/10.1159/000324927
work_keys_str_mv AT gliemmichael cerebellardegenerationaspresentingsymptomofrecurrentendometrialstromalsarcomawithsexcordelements
AT panayotopoulosdimitris cerebellardegenerationaspresentingsymptomofrecurrentendometrialstromalsarcomawithsexcordelements
AT feindtpeter cerebellardegenerationaspresentingsymptomofrecurrentendometrialstromalsarcomawithsexcordelements
AT heikaussebastian cerebellardegenerationaspresentingsymptomofrecurrentendometrialstromalsarcomawithsexcordelements
AT fleischmarkusc cerebellardegenerationaspresentingsymptomofrecurrentendometrialstromalsarcomawithsexcordelements
AT seitzrudigerj cerebellardegenerationaspresentingsymptomofrecurrentendometrialstromalsarcomawithsexcordelements

Ejemplares similares