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Hydroxyl Radical Modification of Immunoglobulin G Generated Cross-Reactive Antibodies: Its Potential Role in Systemic Lupus Erythematosus

OBJECTIVE: Role of reactive oxygen species (ROS) modified human Immunoglobulin G (IgG) in systemic lupus erythematosus (SLE) has been investigated. METHODS: Human IgG was modified by hydroxyl-radicals. Immunogenicity of native and modified human IgG was probed by inducing polyclonal antibodies in ra...

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Detalles Bibliográficos
Autores principales:	Al-Shobaili, Hani A., Al Robaee, Ahmad A., Alzolibani, Abdullateef, Khan, Muhammad Ismail, Rasheed, Zafar
Formato:	Texto
Lenguaje:	English
Publicado:	Libertas Academica 2011
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072208/ https://www.ncbi.nlm.nih.gov/pubmed/21487454 http://dx.doi.org/10.4137/CMAMD.S6793

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