The XLMR gene PHF8 encodes a histone H4K20/H3K9 demethylase and regulates zebrafish brain and craniofacial development

X-linked mental retardation (XLMR) is a complex human disease that causes intellectual disability1. Causal mutations have been found in approximately 90 X-linked genes2; however, molecular and biological functions of many of these genetically defined XLMR genes remain unknown. PHF8 (PHD Finger 8) is...

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Detalles Bibliográficos
Autores principales: Qi, Hank H., Sarkissian, Madathia, Hu, Gang-Qing, Wang, Zhibin, Bhattacharjee, Arindam, Gordon, D. Benjamin, Gonzales, Michelle, Lan, Fei, Ongusaha, Pat P., Huarte, Maite, Yaghi, Nasser K., Lim, Huijun, Garcia, Benjamin A., Brizuela, Leonardo, Zhao, Keji, Roberts, Thomas M., Shi, Yang
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072215/
https://www.ncbi.nlm.nih.gov/pubmed/20622853
http://dx.doi.org/10.1038/nature09261

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