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Singlet oxygen mediated DNA degradation by copper nanoparticles: potential towards cytotoxic effect on cancer cells
The DNA degradation potential and anti-cancer activities of copper nanoparticles of 4-5 nm size are reported. A dose dependent degradation of isolated DNA molecules by copper nanoparticles through generation of singlet oxygen was observed. Singlet oxygen scavengers such as sodium azide and Tris [hyd...
Autores principales: | Jose, Gregor P, Santra, Subhankar, Mandal, Swadhin K, Sengupta, Tapas K |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072310/ https://www.ncbi.nlm.nih.gov/pubmed/21439072 http://dx.doi.org/10.1186/1477-3155-9-9 |
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