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Nuclear envelope structural defects cause chromosomal numerical instability and aneuploidy in ovarian cancer

BACKGROUND: Despite our substantial understanding of molecular mechanisms and gene mutations involved in cancer, the technical approaches for diagnosis and prognosis of cancer are limited. In routine clinical diagnosis of cancer, the procedure is very basic: nuclear morphology is used as a common as...

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Detalles Bibliográficos
Autores principales: Capo-chichi, Callinice D, Cai, Kathy Q, Simpkins, Fiona, Ganjei-Azar, Parvin, Godwin, Andrew K, Xu, Xiang-Xi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072346/
https://www.ncbi.nlm.nih.gov/pubmed/21439080
http://dx.doi.org/10.1186/1741-7015-9-28