Quantitative Fitness Analysis Shows That NMD Proteins and Many Other Protein Complexes Suppress or Enhance Distinct Telomere Cap Defects

To better understand telomere biology in budding yeast, we have performed systematic suppressor/enhancer analyses on yeast strains containing a point mutation in the essential telomere capping gene CDC13 (cdc13-1) or containing a null mutation in the DNA damage response and telomere capping gene YKU...

Descripción completa

Detalles Bibliográficos
Autores principales: Addinall, Stephen Gregory, Holstein, Eva-Maria, Lawless, Conor, Yu, Min, Chapman, Kaye, Banks, A. Peter, Ngo, Hien-Ping, Maringele, Laura, Taschuk, Morgan, Young, Alexander, Ciesiolka, Adam, Lister, Allyson Lurena, Wipat, Anil, Wilkinson, Darren James, Lydall, David
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072368/
https://www.ncbi.nlm.nih.gov/pubmed/21490951
http://dx.doi.org/10.1371/journal.pgen.1001362

Ejemplares similares

Ejemplares similares