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Survival Motor Neuron Protein Regulates Stem Cell Division, Proliferation, and Differentiation in Drosophila
Spinal muscular atrophy is a severe neurogenic disease that is caused by mutations in the human survival motor neuron 1 (SMN1) gene. SMN protein is required for the assembly of small nuclear ribonucleoproteins and a dramatic reduction of the protein leads to cell death. It is currently unknown how t...
Autores principales: | Grice, Stuart J., Liu, Ji-Long |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072375/ https://www.ncbi.nlm.nih.gov/pubmed/21490958 http://dx.doi.org/10.1371/journal.pgen.1002030 |
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