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Down-Regulation of the Canonical Wnt β-Catenin Pathway in the Airway Epithelium of Healthy Smokers and Smokers with COPD

BACKGROUND: The Wnt pathway mediates differentiation of epithelial tissues; depending on the tissue types, Wnt can either drive or inhibit the differentiation process. We hypothesized that key genes in the Wnt pathway are suppressed in the human airway epithelium under the stress of cigarette smokin...

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Detalles Bibliográficos
Autores principales:	Wang, Rui, Ahmed, Joumana, Wang, Guoqing, Hassan, Ibrahim, Strulovici-Barel, Yael, Hackett, Neil R., Crystal, Ronald G.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072378/ https://www.ncbi.nlm.nih.gov/pubmed/21490961 http://dx.doi.org/10.1371/journal.pone.0014793

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