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Repeated administration of the GABA(B) receptor positive modulator BHF177 decreased nicotine self-administration, and acute administration decreased cue-induced reinstatement of nicotine seeking in rats

RATIONALE: γ-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the brain and is implicated in the modulation of central reward processes. Acute or chronic administration of GABA(B) receptor agonists or positive modulators decreased self-administration of various drugs of abuse. Fu...

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Detalles Bibliográficos
Autores principales:	Vlachou, Styliani, Guery, Sebastien, Froestl, Wolfgang, Banerjee, Deboshri, Benedict, Jessica, Finn, M. G., Markou, Athina
Formato:	Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2010
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072487/ https://www.ncbi.nlm.nih.gov/pubmed/21181127 http://dx.doi.org/10.1007/s00213-010-2119-x

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