Permeability of dura mater: a possible link between cortical spreading depression and migraine pain? A comment

In the wake of cortical spreading depression (CSD) it has been suggested that noxious substances diffuse through the dura with resulting firing of epidural nerves. In my view this is unlikely because there are good reasons to suggest that there must be a dura-brain barrier. Alternatively collateral...

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Detalles Bibliográficos
Autor principal: Tfelt-Hansen, Peer Carsten
Formato: Texto
Lenguaje:English
Publicado: Springer Milan 2010
Materias:
Editorial Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072496/
https://www.ncbi.nlm.nih.gov/pubmed/20821244
http://dx.doi.org/10.1007/s10194-010-0252-x
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author Tfelt-Hansen, Peer Carsten
author_facet Tfelt-Hansen, Peer Carsten
author_sort Tfelt-Hansen, Peer Carsten
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description In the wake of cortical spreading depression (CSD) it has been suggested that noxious substances diffuse through the dura with resulting firing of epidural nerves. In my view this is unlikely because there are good reasons to suggest that there must be a dura-brain barrier. Alternatively collateral branches from the trigeminal nerve to the pia and the dura may signal what is happening with ions and substances on the brain surface during CSD to the epidural space.
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spelling pubmed-30724962011-05-18 Permeability of dura mater: a possible link between cortical spreading depression and migraine pain? A comment Tfelt-Hansen, Peer Carsten J Headache Pain Editorial Commentary In the wake of cortical spreading depression (CSD) it has been suggested that noxious substances diffuse through the dura with resulting firing of epidural nerves. In my view this is unlikely because there are good reasons to suggest that there must be a dura-brain barrier. Alternatively collateral branches from the trigeminal nerve to the pia and the dura may signal what is happening with ions and substances on the brain surface during CSD to the epidural space. Springer Milan 2010-09-07 2011-02 /pmc/articles/PMC3072496/ /pubmed/20821244 http://dx.doi.org/10.1007/s10194-010-0252-x Text en © Springer-Verlag 2010
spellingShingle Editorial Commentary
Tfelt-Hansen, Peer Carsten
Permeability of dura mater: a possible link between cortical spreading depression and migraine pain? A comment
title Permeability of dura mater: a possible link between cortical spreading depression and migraine pain? A comment
title_full Permeability of dura mater: a possible link between cortical spreading depression and migraine pain? A comment
title_fullStr Permeability of dura mater: a possible link between cortical spreading depression and migraine pain? A comment
title_full_unstemmed Permeability of dura mater: a possible link between cortical spreading depression and migraine pain? A comment
title_short Permeability of dura mater: a possible link between cortical spreading depression and migraine pain? A comment
title_sort permeability of dura mater: a possible link between cortical spreading depression and migraine pain? a comment
topic Editorial Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072496/
https://www.ncbi.nlm.nih.gov/pubmed/20821244
http://dx.doi.org/10.1007/s10194-010-0252-x
work_keys_str_mv AT tfelthansenpeercarsten permeabilityofduramaterapossiblelinkbetweencorticalspreadingdepressionandmigrainepainacomment

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