Thioredoxin-binding protein-2 (TBP-2/VDUP1/TXNIP) regulates T-cell sensitivity to glucocorticoid during HTLV-I-induced transformation

Although glucocorticoid (GC) is widely used for treating hematopoietic malignancies including adult T-cell leukemia (ATL), the mechanism by which leukemic cells become resistant to GC in the clinical course remains unclear. Using a series of T-cell lines infected with human T lymphotropic virus type...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Z, Lopez-Ramos, D A, Yoshihara, E, Maeda, Y, Masutani, H, Sugie, K, Maeda, M, Yodoi, J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072512/
https://www.ncbi.nlm.nih.gov/pubmed/21151022
http://dx.doi.org/10.1038/leu.2010.286

Ejemplares similares

Ejemplares similares