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Stem cell niches and other factors that influence the sensitivity of bone marrow to radiation-induced bone cancer and leukaemia in children and adults
Purpose: This paper reviews and reassesses the internationally accepted niches or ‘targets’ in bone marrow that are sensitive to the induction of leukaemia and primary bone cancer by radiation. Conclusions: The hypoxic conditions of the 10 μm thick endosteal/osteoblastic niche where preleukemic stem...
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Formato: | Texto |
Lenguaje: | English |
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Informa Healthcare
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072695/ https://www.ncbi.nlm.nih.gov/pubmed/21204614 http://dx.doi.org/10.3109/09553002.2010.537430 |