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The anti-inflammatory effects of dimethyl fumarate in astrocytes involve glutathione and haem oxygenase-1

DMF (dimethyl fumarate) exerts anti-inflammatory and pro-metabolic effects in a variety of cell types, and a formulation (BG-12) is being evaluated for monotherapy in multiple sclerosis patients. DMF modifies glutathione (GSH) levels that can induce expression of the anti-inflammatory protein HO-1 (...

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Detalles Bibliográficos
Autores principales:	Lin, Shao Xia, Lisi, Lucia, Dello Russo, Cinzia, Polak, Paul E, Sharp, Anthony, Weinberg, Guy, Kalinin, Sergey, Feinstein, Douglas L
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Neurochemistry 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072764/ https://www.ncbi.nlm.nih.gov/pubmed/21382015 http://dx.doi.org/10.1042/AN20100033

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