Cargando…

A genetic variant in the APE1/Ref-1 gene promoter -141T/G may modulate risk of glioblastoma in a Chinese Han population

BACKGROUND: The human apurinic/apyrimidinic endonuclease 1/Redox effector factor-1 (APE1/Ref-1) is implicated in tumor development and progression. Recently, the APE1/Ref-1 promoter -141T/G variant (rs1760944) has been reported to be associated with lung cancer risk. Given the importance of APE1/Ref...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Keke, Hu, Dezhi, Lu, Juan, Fan, Weiwei, Liu, Hongliang, Chen, Hongyan, Chen, Gong, Wei, Qingyi, Du, Guhong, Mao, Ying, Lu, Daru, Zhou, Liangfu
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3072948/ https://www.ncbi.nlm.nih.gov/pubmed/21429202 http://dx.doi.org/10.1186/1471-2407-11-104

Ejemplares similares

APE1/Ref-1 Role in Inflammation and Immune Response
por: Oliveira, Thais Teixeira, et al.
Publicado: (2022)

Elevation of Serum APE1/Ref-1 in Experimental Murine Myocarditis
por: Jin, Seon-Ah, et al.
Publicado: (2017)

APE1/Ref-1 as a Novel Target for Retinal Diseases
por: Heisel, Curtis, et al.
Publicado: (2021)

New Horizons for the Roles and Association of APE1/Ref-1 and ABCA1 in Atherosclerosis
por: Chen, Wujun, et al.
Publicado: (2021)

APE1/Ref-1 Regulates STAT3 Transcriptional Activity and APE1/Ref-1–STAT3 Dual-Targeting Effectively Inhibits Pancreatic Cancer Cell Survival
por: Cardoso, Angelo A., et al.
Publicado: (2012)

The role of APE/Ref-1 signaling pathway in hepatocellular carcinoma progression
por: YANG, ZHEN, et al.
Publicado: (2014)

Urinary APE1/Ref-1: A Potential Bladder Cancer Biomarker
por: Choi, Sunga, et al.
Publicado: (2016)

Dynamic Regulation of APE1/Ref-1 as a Therapeutic Target Protein
por: Choi, Sunga, et al.
Publicado: (2016)

APE1/Ref-1 as a Serological Biomarker for the Detection of Bladder Cancer
por: Shin, Ju Hyun, et al.
Publicado: (2015)

APE1/Ref-1 as a Therapeutic Target for Inflammatory Bowel Disease
por: Sahakian, Lauren, et al.
Publicado: (2023)

Activation of NRF2 by APE1/REF1 is redox-dependent in Barrett's related esophageal adenocarcinoma cells
por: Sriramajayam, Kannappan, et al.
Publicado: (2021)

Identification of a novel potential antitumor activity of gossypol as an APE1/Ref-1 inhibitor
por: Qian, Chengyuan, et al.
Publicado: (2014)

Fine Mapping of a Region of Chromosome 11q23.3 Reveals Independent Locus Associated with Risk of Glioma
por: Chen, Hongyan, et al.
Publicado: (2012)

Plasma APE1/Ref-1 Correlates with Atherosclerotic Inflammation in ApoE(−/−) Mice
por: Lee, Yu Ran, et al.
Publicado: (2020)

Inhibition of APE1/Ref-1 for Neovascular Eye Diseases: From Biology to Therapy
por: Hartman, Gabriella D., et al.
Publicado: (2021)

Bis-Cinnamamide Derivatives as APE/Ref-1 Inhibitors for the Treatment of Human Melanoma
por: Alhazmi, Razan, et al.
Publicado: (2022)

Analysis of nuclear transport signals in the human apurinic/apyrimidinic endonuclease (APE1/Ref1)
por: Jackson, Elias B., et al.
Publicado: (2005)

DNA Repair and Cancer Therapy: Targeting APE1/Ref-1 Using Dietary Agents
por: Raffoul, Julian J., et al.
Publicado: (2012)

APE1/Ref-1 – One Target with Multiple Indications: Emerging Aspects and New Directions
por: Mijit, Mahmut, et al.
Publicado: (2021)

Identification of Novel Pathways Regulated by APE1/Ref-1 in Human Retinal Endothelial Cells
por: Mijit, Mahmut, et al.
Publicado: (2023)

Nitric oxide controls nuclear export of APE1/Ref-1 through S-nitrosation of Cysteines 93 and 310
por: Qu, Jing, et al.
Publicado: (2007)

Exploiting the Ref-1-APE1 node in cancer signaling and other diseases: from bench to clinic
por: Shah, Fenil, et al.
Publicado: (2017)

ATP Binding Cassette Transporter A1 is Involved in Extracellular Secretion of Acetylated APE1/Ref-1
por: Lee, Yu Ran, et al.
Publicado: (2019)

APE1/Ref-1 as an emerging therapeutic target for various human diseases: phytochemical modulation of its functions
por: Thakur, Shweta, et al.
Publicado: (2014)

Elevated APE1/Ref-1 Levels of Synovial Fluids in Patients with Rheumatoid Arthritis: Reflection of Disease Activity
por: Yoo, In Seol, et al.
Publicado: (2021)

Activation of APE1/Ref-1 is dependent on reactive oxygen species generated after purinergic receptor stimulation by ATP
por: Pines, Alex, et al.
Publicado: (2005)

Transcriptional Up-Regulation of APE1/Ref-1 in Hepatic Tumor: Role in Hepatocytes Resistance to Oxidative Stress and Apoptosis
por: Di Maso, Vittorio, et al.
Publicado: (2015)

APE1/Ref-1 Inhibits Phosphate-Induced Calcification and Osteoblastic Phenotype Changes in Vascular Smooth Muscle Cells
por: Lee, Ki Mo, et al.
Publicado: (2017)

Dual Regulatory Roles of Human AP-Endonuclease (APE1/Ref-1) in CDKN1A/p21 Expression
por: Sengupta, Shiladitya, et al.
Publicado: (2013)

APE1/Ref-1 Inhibits Adipogenic Transcription Factors during Adipocyte Differentiation in 3T3-L1 Cells
por: Lee, Eun-Ok, et al.
Publicado: (2023)

Effects of gemcitabine on APE/ref-1 endonuclease activity in pancreatic cancer cells, and the therapeutic potential of antisense oligonucleotides
por: Lau, J P, et al.
Publicado: (2004)

Inhibition of APE1/Ref-1 redox activity rescues human retinal pigment epithelial cells from oxidative stress and reduces choroidal neovascularization
por: Li, Y., et al.
Publicado: (2014)

Regulation of the human AP-endonuclease (APE1/Ref-1) expression by the tumor suppressor p53 in response to DNA damage
por: Zaky, Amira, et al.
Publicado: (2008)

Knock-in reconstitution studies reveal an unexpected role of Cys-65 in regulating APE1/Ref-1 subcellular trafficking and function
por: Vascotto, Carlo, et al.
Publicado: (2011)

Altered Secretory Activity of APE1/Ref-1 D148E Variants Identified in Human Patients With Bladder Cancer
por: Lee, Yu Ran, et al.
Publicado: (2016)

Dual Function of Secreted APE1/Ref-1 in TNBC Tumorigenesis: An Apoptotic Initiator and a Regulator of Chronic Inflammatory Signaling
por: Choi, Sunga, et al.
Publicado: (2022)

Secreted APE1/Ref-1 inhibits TNF-α-stimulated endothelial inflammation via thiol-disulfide exchange in TNF receptor
por: Park, Myoung Soo, et al.
Publicado: (2016)

Therapeutic positioning of secretory acetylated APE1/Ref-1 requirement for suppression of tumor growth in triple-negative breast cancer in vivo
por: Lee, Yu Ran, et al.
Publicado: (2018)

Editor's Note to ‘Activation of APE1/Ref-1 is dependent on reactive oxygen species generated after purinergic receptor stimulation by ATP’
Publicado: (2022)

A common polymorphism rs3781637 in MTNR1B is associated with type 2 diabetes and lipids levels in Han Chinese individuals
por: Ling, Yan, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_v3i8ccucef2u3j0r5ujf4qamsm