Potent Inhibition of Heterotopic Ossification by Nuclear Retinoic Acid Receptor γ Agonists

Heterotopic ossification (HO) consists of ectopic bone formation within soft tissues following surgery or trauma and can have debilitating consequences, but no definitive cure is available. Here we show that HO was essentially prevented in mice receiving nuclear retinoic acid receptor γ (RARγ) agoni...

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Detalles Bibliográficos
Autores principales: Shimono, Kengo, Tung, Wei-en, Macolino, Christine, Chi, Amber Hsu-Tsai, Didizian, Johanna J., Mundy, Christina, Chandraratna, Roshantha A., Mishina, Yuji, Iwamoto, Motomi Enomoto, Pacifici, Maurizio, Iwamoto, Masahiro
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073031/
https://www.ncbi.nlm.nih.gov/pubmed/21460849
http://dx.doi.org/10.1038/nm.2334

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