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lncRNAs transactivate Staufen1-mediated mRNA decay by duplexing with 3'UTRs via Alu elements
Staufen1 (STAU1)-mediated mRNA decay (SMD) degrades translationally active mRNAs that bind the double-stranded (ds)RNA binding protein STAU1 within their 3'-untranslated regions (3'UTRs)1,2. Earlier studies defined the STAU1 binding site (SBS) within ADP ribosylation factor 1 (ARF1) mRNA a...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073508/ https://www.ncbi.nlm.nih.gov/pubmed/21307942 http://dx.doi.org/10.1038/nature09701 |