Hepatosplenic Gamma/Delta T-Cell Lymphoma Masquerading as Alcoholic Hepatitis and Methadone Withdrawal

Hepatosplenic gamma/delta T-cell lymphoma is a rare neoplasm of mature gamma/delta T-cells with sinusoidal infiltration of spleen, liver, and bone marrow. Patients are predominantly adolescent and young adult males and usually present with marked hepatosplenomegaly. Pancytopenia is another common fi...

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Detalles Bibliográficos
Autores principales: Morra, H.A. Lopez, Fine, S.N., Dickstein, G.
Formato: Texto
Lenguaje:English
Publicado: S. Karger AG 2007
Materias:
Published: September 2007
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073793/
https://www.ncbi.nlm.nih.gov/pubmed/21487551
http://dx.doi.org/10.1159/000107654
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author Morra, H.A. Lopez
Fine, S.N.
Dickstein, G.
author_facet Morra, H.A. Lopez
Fine, S.N.
Dickstein, G.
author_sort Morra, H.A. Lopez
collection PubMed
description Hepatosplenic gamma/delta T-cell lymphoma is a rare neoplasm of mature gamma/delta T-cells with sinusoidal infiltration of spleen, liver, and bone marrow. Patients are predominantly adolescent and young adult males and usually present with marked hepatosplenomegaly. Pancytopenia is another common finding. Despite an initial response to treatment, patients have a median survival of one to two years. In this report, we document a case of alcoholic hepatitis and methadone withdrawal masquerading unsuspected, hepatosplenic gamma/delta T-cell lymphoma with unusual CD20 positivity.
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spelling pubmed-30737932011-04-12 Hepatosplenic Gamma/Delta T-Cell Lymphoma Masquerading as Alcoholic Hepatitis and Methadone Withdrawal Morra, H.A. Lopez Fine, S.N. Dickstein, G. Case Rep Gastroenterol Published: September 2007 Hepatosplenic gamma/delta T-cell lymphoma is a rare neoplasm of mature gamma/delta T-cells with sinusoidal infiltration of spleen, liver, and bone marrow. Patients are predominantly adolescent and young adult males and usually present with marked hepatosplenomegaly. Pancytopenia is another common finding. Despite an initial response to treatment, patients have a median survival of one to two years. In this report, we document a case of alcoholic hepatitis and methadone withdrawal masquerading unsuspected, hepatosplenic gamma/delta T-cell lymphoma with unusual CD20 positivity. S. Karger AG 2007-09-20 /pmc/articles/PMC3073793/ /pubmed/21487551 http://dx.doi.org/10.1159/000107654 Text en Copyright © 2007 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published: September 2007
Morra, H.A. Lopez
Fine, S.N.
Dickstein, G.
Hepatosplenic Gamma/Delta T-Cell Lymphoma Masquerading as Alcoholic Hepatitis and Methadone Withdrawal
title Hepatosplenic Gamma/Delta T-Cell Lymphoma Masquerading as Alcoholic Hepatitis and Methadone Withdrawal
title_full Hepatosplenic Gamma/Delta T-Cell Lymphoma Masquerading as Alcoholic Hepatitis and Methadone Withdrawal
title_fullStr Hepatosplenic Gamma/Delta T-Cell Lymphoma Masquerading as Alcoholic Hepatitis and Methadone Withdrawal
title_full_unstemmed Hepatosplenic Gamma/Delta T-Cell Lymphoma Masquerading as Alcoholic Hepatitis and Methadone Withdrawal
title_short Hepatosplenic Gamma/Delta T-Cell Lymphoma Masquerading as Alcoholic Hepatitis and Methadone Withdrawal
title_sort hepatosplenic gamma/delta t-cell lymphoma masquerading as alcoholic hepatitis and methadone withdrawal
topic Published: September 2007
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073793/
https://www.ncbi.nlm.nih.gov/pubmed/21487551
http://dx.doi.org/10.1159/000107654
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AT finesn hepatosplenicgammadeltatcelllymphomamasqueradingasalcoholichepatitisandmethadonewithdrawal
AT dicksteing hepatosplenicgammadeltatcelllymphomamasqueradingasalcoholichepatitisandmethadonewithdrawal

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