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Replicase-based plasmid DNA shows anti-tumor activity

BACKGROUND: Double stranded RNA (dsRNA) has multiple anti-tumor mechanisms. Over the past several decades, there have been numerous attempts to utilize synthetic dsRNA to control tumor growth in animal models and clinical trials. Recently, it became clear that intracellular dsRNA is more effective t...

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Detalles Bibliográficos
Autores principales: Rodriguez, B Leticia, Yu, Zhen, Chung, Woon-Gye, Weiss, Richard, Cui, Zhengrong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073940/
https://www.ncbi.nlm.nih.gov/pubmed/21443770
http://dx.doi.org/10.1186/1471-2407-11-110