Particulate Matter-Induced Lung Inflammation Increases Systemic Levels of PAI-1 and Activates Coagulation Through Distinct Mechanisms

BACKGROUND: Exposure of human populations to ambient particulate matter (PM) air pollution significantly contributes to the mortality attributable to ischemic cardiovascular events. We reported that mice treated with intratracheally instilled PM develop a prothrombotic state that requires the releas...

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Detalles Bibliográficos
Autores principales: Budinger, G. R. Scott, McKell, Joanne L., Urich, Daniela, Foiles, Nancy, Weiss, Ivy, Chiarella, Sergio E., Gonzalez, Angel, Soberanes, Saul, Ghio, Andrew J., Nigdelioglu, Recep, Mutlu, Ece A., Radigan, Kathryn A., Green, David, Kwaan, Hau C., Mutlu, Gökhan M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073968/
https://www.ncbi.nlm.nih.gov/pubmed/21494547
http://dx.doi.org/10.1371/journal.pone.0018525

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