Rgs2 Mediates Pro-Angiogenic Function of Myeloid Derived Suppressor Cells in the Tumor Microenvironment via Upregulation of MCP-1

BACKGROUND: Tumor growth is intimately linked with stromal interactions. Myeloid derived suppressor cells (MDSCs) are dramatically elevated in cancer patients and tumor bearing mice. MDSCs modulate the tumor microenvironment through attenuating host immune response and increasing vascularization. ME...

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Detalles Bibliográficos
Autores principales: Boelte, Kimberly C., Gordy, Laura E., Joyce, Sebastian, Thompson, Mary Ann, Yang, Li, Lin, P. Charles
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073977/
https://www.ncbi.nlm.nih.gov/pubmed/21494556
http://dx.doi.org/10.1371/journal.pone.0018534

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