CD8(+) T Cells and IFN-γ Mediate the Time-Dependent Accumulation of Infected Red Blood Cells in Deep Organs during Experimental Cerebral Malaria

BACKGROUND: Infection with Plasmodium berghei ANKA (PbA) in susceptible mice induces a syndrome called experimental cerebral malaria (ECM) with severe pathologies occurring in various mouse organs. Immune mediators such as T cells or cytokines have been implicated in the pathogenesis of ECM. Red blo...

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Detalles Bibliográficos
Autores principales: Claser, Carla, Malleret, Benoît, Gun, Sin Yee, Wong, Alicia Yoke Wei, Chang, Zi Wei, Teo, Pearline, See, Peter Chi Ee, Howland, Shanshan Wu, Ginhoux, Florent, Rénia, Laurent
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073989/
https://www.ncbi.nlm.nih.gov/pubmed/21494565
http://dx.doi.org/10.1371/journal.pone.0018720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073989/
https://www.ncbi.nlm.nih.gov/pubmed/21494565
http://dx.doi.org/10.1371/journal.pone.0018720

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